In part I, hazards of chemical pollutants in the organism are reviewed. The effect of toxic substances, allergens and carcinogens in industrial medicine and the handling of chemical pollutants are both examined. A list of legal regulations and literature references is provided. In part II, toxic substances and substances causing injury to the skin and mucosa are discussed. Various skin protective ointments are listed. Reference is made to allergens and carcinogens, and the danger of lead to health is examined. -- AATA