Influenced by mutual effect of the physiogeologic process, human activity and environment, the Great Wall in Gansu Province were destroyed seriously and urgent to be conserved. Therefore, various era of Great Wall’s distribution and its present situation were investigated. The result of analyse indicate that the main diseases were serious weathering, the foundation indent due to wind erosion, washing out and capillary, fissure, collapse and sloughing, human destruction. To solve the problems, suggestions were put forward such as onsolidated subsoil consolidation using mud brick and static pressure grouting technique, anchoring, crack grouting, penetrating grouting on the surface, anchoring and grouting. The Great Wall of Han Dynasty in Guangchangsui ruins and the Majiashan ruins of the Qin Dynasty in the Waring States Period were introduced to illustrate the conservation of Great Wall. The results indicated that the suggestions were of important reference to reinforce the earthen Great Wall.