This paper will describe a recently observed phenomenon in a manuscript from the 16th century written by Wenzel Jamnitzer, a German goldsmith. It has been observed that, within the book, large areas of the lead white pigment have blackened. However, areas of the lead white which corresponded directly to iron gall ink inscriptions on the reverse of the same sheet are not blackened. Effectively a ghost image of the inscriptions can be seen running through the otherwise discoloured lead white pigment. This paper will present the results of the analysis of the various pigments, using Raman microscopy and X-ray fluorescence. The analysis confirms the presence of lead white and other pigments including the little-known pigment, mosaic gold (tin disulfide). In situ identification of blackened lead white, i.e. lead sulfide was obtained for the first time. We also suggest mechanisms for the ghost image effect and offer observations as to the possible source of the lead white discolouration. -- SCMRE