Organosilanes (silanes) are compounds containing silicon and organic functional groups. Their bifunctionality makes them ideal coupling agents for normally incompatible materials such as glass and organic resins. This study focuses on the use of one organosilane, 3-Glycidoxypropltrimethoxy silane, for the consolidation of flaking gelatin emulsion on glass plate negatives. In the study, experimental emulsion samples were adhered to glass microscope slides using various treatment protocols. Results on experimental samples indicate that the silane was effective as a consolidant. Consolidation of actual glass plate negatives was achieved with limited success. The silane passed the ANSI IT9.2 Photo Activity Test. The use of any silane is not considered to be readily reversible.