Human population movements into and around the outer Shumagin Islands of southwestern Alaska during the last 5000 years, and temporal gaps in Shumagin habitation correlate inversely with geologically inferred prehistoric earthquakes. Clusters of inferred seismic activity correlate with temporal gaps or with small, sparsely distributed archaeological sites; periods of relative seismic quiescence coincide with settlement florescence. Variations in terrace and archaeological site heights across the study area indicate differential uplift of the outer Shumagin Islands when corrected for the Holocene sea level rise and post-glacial isostatic adjustments.