Scope of the work was the restauration, reconstruction and completion of the St. Claire’s former Convent, with an overall budget of 5,000,000 euro within the Program for the Thousand-year-celebration of the city of Gorizia. Main activities regarded the overall convent facility restauration, the reconstruction of the electrical and mechanical systems, the sismic and functional adaptations. The new building use addresses to University courses and Research activities for Cultural Heritage Operators of the Liberal Arts School of Udine, for the Librarianship Preservation Laboratory and for Translators Schools. The paper highlights the integration between the restauration works and the HVAC systems used to meet the best energy effiencies and savings.