A program of experimental researches on the seismic behaviour of full-scale stone masonry panels is explained. This program was developed at the University of Florence, Department of Civil Engineering, as part of the C.N.R. G.N.D.T. - Subproject 2: Prevention of Building Damage - Working Group 2.2: Experimental Evaluation of the Seismic Behaviour of Structures coordinated research program. The main objective of this part of the project is to investigate the seismic behaviour of commonly used masonry typologies in the Florence area. Both cyclic and monotonic tests are designed to assess the mechanical characteristics of stone masonry and its strength under cyclic actions. Evaluation of flexural and shear capacity, load degradation, ductility and energy dissipation was also provided. This paper presents the setup of two different experimental tests and describes the used laboratory equipment.