Wrought-iron artillery was introduced to European and Near Eastern armies and navies in the 14th Century. Between ca. A.D. 1350 and 1550, it flourished, and became obsolete. This class of early gunpowder weaponry was relied on extensively throughout this crucial period as one of the prime instruments of political policy enforcement. Detailed studies of the variation, construction, composition, and capabilities of these critical weapons systems have only begun within the last 15 years. Relatively few wrought-iron cannon are known to exist worldwide; of these, the largest single assemblage was discovered at a shipwreck site in the northeastern Caribbean. Macroanalyses of specific examples of these guns and associated projectiles from the Molasses Reef Wreck have produced evidence of their method of manufacture and generated new ideas regarding their development and employment. A brief historical background on the innovation of wrought-iron artillery, and the difficulties encountered in reconciling historical description with present-day observation and wisdom on the subject, are presented. Last, hypothetical construction techniques, utilized in a selected specimen from the Molasses Reef Wreck assemblage, are discussed in detail.