A study was made of 14 workers at a factory producing simulated leather and cloth treated with resins dissolved in various solvents, including dimethylformamide. Irritation of the eyes, upper airways and digestive tract and intolerance to alcohol were the main pathological symptoms; evidence of liver disease was less pronounced. In one case, which was observed at greater length, the signs of hepatolysis and cholestasis disappeared quickly after interruption of exposure. Control of environmental concentrations of the solvent at the workplace revealed that excursions of double the safety limit were possible. -- AATA