Factors which must be considered in the design of a low-power micromanipulator are discussed. A rough prototype model is described and it is shown how the final instrument was evolved from this. The instrument is completely three-dimensional, will follow a movement of the hand with a reduction ratio of 4 to 1, and will stay put in any position. It is intended for use at magnifications up to 200 times, and the movenent, as seen through a binocular dissection microscope, is not reversed.