As a result of the 2011 earthquake, approximately 20 buildings in the Washington, D.C., area suffered some form of damage. Damages ranged from superficial plaster cracking to major structural issues. Within days of the earthquake, teams of engineers were assessing all of the Smithsonian buildings. For the most part, damage was determined to be repairable during the year or was postponed to coincide with either scheduled renovation or systems upgrade work in the next few years when funding would become available. While the structural evaluations and major work were carried out by personnel from the Office of Facilities, Engineering and Operations (OFEO) and contractors, all collections damage assessments were conducted mainly by Smithsonian collections management and conservation staff. Within hours of the earthquake, the National Collections Program (NCP) issued a request for a collections damage assessment to the heads of collections of each Smithsonian collecting unit. Within days, the NCP provided rolling updates to the Smithsonian’s Emergency Operation Center to inform it regarding the immediate- and longer-term response effort that would be required to ensure the continued safety of collections. This report highlights the approach taken in evaluating the damage to both structures and collections to organize and efficiently prioritize the required actions to address the suffered damage.